Membrane fusion mediated by ricin and viscumin.
نویسندگان
چکیده
The ribosome inactivating plant proteins (RIPs) ricin and viscumin but not Ricinus communis agglutinin are able induce vesicle-vesicle fusion. A model is suggested in which the toxicity of the RIPs is partially determined by their fusogenicity. Herein, fusion is hypothesized to allow the RIPs to leak across endocytic vesicles to approve their access to cytoplasmic ribosomes.
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عنوان ژورنال:
- Biochimica et biophysica acta
دوره 1371 1 شماره
صفحات -
تاریخ انتشار 1998